About tmRDB

The tmRDB is a tool in the study of the structures and functions of the tmRNA (earlier called "10S RNA"). As the name implies, tmRNA has properties of tRNA and mRNA combined in a single molecule. The tmRDB provides aligned, annotated and phylogenetically ordered tmRNA sequences. The alignments of the sequences represent conserved secondary structure elements where each base pair is proven by comparative sequence analysis. Where possible, we established direct links to primary sources.

marks a recently added entry.
marks a new sequence. (See database issue of Nucleic Acids Research.)
marks an updated entry.
marks a clickable note.

If your research is assisted by the tmRDB, please refer to: Zwieb, C., Gorodkin, J., Knudsen B., Burks, J., and Wower, J. (2003) tmRDB (tmRNA database) Nucleic Acids Res, 31, 446-447. [Abstract] [Full-text PDF] version of this paper reproduced with permission from NAR Online.

Review of tmRNA secondary structure in: C. Zwieb, I. Wower and J. Wower (1999) "Comparative sequence analysis of tmRNA" Nucleic Acids Research, 27, 2063-2071. Full-text PDF of this paper (943 KB), reproduced with permission from NAR Online

Direct data submissions, questions, complaints, suggestions, etc. about tmRDB to:

Christian Zwieb, Department of Molecular Biology
University of Texas Health Science Center at Tyler
11937 US Highway 271
Tyler, Texas 75708-3154, U.S.A.
phone: (903) 877-7689
fax: (903) 877-5731
Email: zwieb@uthct.edu. Web: http://rnp.uthct.edu/zwieb/ZwiebFac.html

For specific questions, contact the tmRDB associates:

Jody Burks

Jan Gorodkin

Niels Larsen

Jesper Cairo Westergaard

Iwona Wower

Jacek Wower

We gratefully acknowledge important contributions by:

Florian Müller for ERNA-3D modeling software

Ingolf Sommer for VCMD molecular dynamics software

Please don't forget to cite the original authors in case you fetch and use data that we only redistribute.

We acknowledge support provided by the National Institutes of Health and the Danish Technical Research Council.

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© Created by Christian Zwieb
zwieb@uthct.edu