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Structures

PDB Component(s) Method Citation PDB-File
Ribosome Binding Domain of the Trigger Factor on the 50S ribosomal subunit from D. radiodurans X-Ray Schlunzen F, Wilson DN, Tian P, Harms JM, McInnes SJ, Hansen HA, Albrecht R, Buerger J, Wilbanks SM, Fucini P.: The binding mode of the trigger factor on the ribosome: implications for protein folding and SRP interaction. Structure 13 pp. 1685 (2005) 2D3O
S-domain of SRP RNA from Methanococcus jannaschii X-Ray Hainzl, T., Huang, S., Sauer-Eriksson, A. E.: Structural Insights into SRP RNA An Induced Fit Mechanism for SRP Assembly RNA 11 pp. 1043 (2005) 1Z43
Ffh-NG/FtsY-NG of Thermus aquaticus X-Ray Egea, P. F., Shan, S. O., Napetschnig, J., Savage, D. F., Walter, P., Stroud, R. M.: Substrate Twinning Activates the Signal Recognition Particle and its Receptor. Nature 427 pp. 215 (2004) 1RJ9
Canine SRP bound to wheat germ ribosome Cryo-EM Halic, M. Becker, T. Pool, M.R. Spahn, C.M. Grassucci, R.A. Frank, J. Beckmann, R. Structure of the signal recognition particle interacting with the elongation-arrested ribosome Nature. v427 pp. 808 (2004) 1RY1
SRP54 of Sulfolobus solfataricus, free and bound to RNA X-Ray Rosendal, K. R., Wild, K., Montoya, G., Sinning, I. Crystal Structure of the Complete Core of Archaeal Signal Recognition Particle and Implications for Interdomain Communication Proc.Nat.Acad.Sci.USA 100 pp. 14701 (2003) 1QZX 1QZW
SRP receptor beta-subunit in complex with the Srx domain from the alpha-subunit of S. cerevisiae X-Ray Schwartz, T., Blobel, G. Structural Basis for the Function of the Beta Subunit of the Eukaryotic Signal Recognition Particle Receptor Cell (Cambridge,Mass.) 112 pp. 793 (2003) 1NRJ
Ternary complex of human SRP19, human SRP54M, and S-domain of human SPP RNA X-Ray Kuglstatter, A., Oubridge, C., Nagai, K. Induced Structural Changes of 7Sl RNA During the Assembly of Human Signal Recognition Particle Nat.Struct.Biol. 9 pp. 740 (2002) 1MFQ
SRP19 of Methanococcus jannaschii bound to the S-domain of human SRP RNA X-Ray Oubridge, C., Kuglstatter, A., Jovine, L., Nagai, K. Crystal Structure of SRP19 in Complex with the S Domain of SRP RNA and its Implication for the Assembly of the Signal Recognition Particle. Mol. Cell 9 pp. 1251 (2002) 1L9A
SRP19 of Methanococcus jannaschii bound to the S-domain of Methanococcus jannaschii SRP RNA X-Ray Hainzl, T., Huang, S., Sauer-Eriksson, A. E. Structure of the Srp19-RNA Complex and Implications for Signal Recognition Particle Assembly Nature 417 pp. 767 (2002) 1LNG
SRP19 of Archaeoglobus fulgidus NMR Pakhomova, O. N., Deep, S., Huang, Q., Zwieb, C., Hinck, A. P. Solution Structure of Protein SRP19 of Archaeoglobus Fulgidus Signal Recognition Particle J.Mol.Biol. 317 pp. 145 (2002) 1KVV 1KVN
Human SRP19 in complex with helix 6 of SRP RNA X-Ray Wild, K., Sinning, I., Cusack, S. Crystal Structure of an Early Protein-RNA Assembly Complex of the Signal Recognition Particle Science 294 pp. 598 (2001) 1JID
Human SRP9/14 in complex with the Alu domain of SRP RNA X-Ray Weichenrieder, O., Wild, K., Strub, K., Cusack, S. Structure and Assembly of the Alu Domain of the Mammalian Signal Recognition Particle Nature 408 pp. 167 (2000) 1E8S 1E8O
E. coli Ffh-M in complex with SRP RNA helix 8 (4.5S RNA) X-Ray Batey, R. T., Rambo, R. P., Lucast, L., Rha, B., Doudna, J. A. Crystal Structure of the Ribonucleoprotein Core of the Signal Recognition Particle. Science 287 pp. 1232 (2000) 1DUL
SRP54-NG of Acidianus ambivalens X-Ray Montoya, G., Te Kaat, K., Moll, R., Schafer, G., Sinning, I. The Crystal Structure of the Conserved Gtpase of Srp54 from the Archaeon Acidianus Ambivalens and its Comparison with Related Structures Suggests a Model for the Srp-Srp Receptor Complex Structure 8 pp. 515 (2000) 1J8M
Helix 8 of E. coli SRP RNA (4.5S) X-Ray L. Jovine, T. Hainzl, C. Oubridge, W. G. Scott, J. Li, T. K. Sixma, A. Wonacott, T. Skarzynski, K. Nagai Structure Fold Des. 15 pp. 527-540 (2000) 1DUH
Human SRP RNA helix 6 X-Ray Wild, K., Weichenrieder, O., Leonard, G. A., Cusack, S. The 2 Angstrom Structure of Helix 6 of the Human Signal Recognition Particle RNA Structure (London) 7 pp. 1345 (1999) 1D4R
E. coli SRP RNA helix 8 NMR Schmitz, U., James, T. L., Lukavsky, P., Walter, P. NMR Structure of the Most Conserved RNA Motif in SRP RNA 28SR 28SP
NG-domain of Thermus aquaticus Ffh with Mg2+GDP and GDP X-Ray Freymann DM, Keenan RJ, Stroud RM, Walter P. Functional changes in the structure of the SRP GTPase on binding GDP and Mg2+GDP. Nat. Struct. Biol. 6 pp. 793 (1999) 2NG1
Human SRP54-M dimer X-Ray Clemons Jr., W. M., Gowda, K., Black, S. D., Zwieb, C., Ramakrishnan, V. Crystal Structure of the Conserved Subdomain of Human Protein Srp54M at 2.1 Angstroms Resolution: Evidence for the Mechanism of Signal Peptide Binding J.Mol.Biol. 292 pp. 697 (1999) 1QB2
Signal peptidase of E. coli with beta-Lactam inhibitor X-Ray Paetzel, M., Dalbey, R. E., Strynadka, N. C. J. Crystal Structure of a Bacterial Signal Peptidase in Complex with a Beta-Lactam Inhibitor Nature 396 pp. 186 (1998) 1B12 1KN9
Thermus aquaticus Ffh trimer X-Ray Keenan, R. J., Freymann, D. M., Walter, P., Stroud, R. M. Crystal Structure of the Signal Sequence Binding Subunit of the Signal Recognition Particle. Cell (Cambridge,Mass.) 94 pp. 181 (1998) 2FFH
Mouse SRP9/14 X-Ray Birse, D. E., Kapp, U., Strub, K., Cusack, S., Aberg, A. The crystal structure of the signal recognition particle Alu RNA binding heterodimer, SRP9/14. EMBO J 16 pp. 3757 (1997) 1914
Ffh-NG of Thermus aquaticus X-Ray Freymann, D. M., Keenan, R. J., Stroud, R. M., Walter, P. Structure of the conserved GTPase domain of the signal recognition particle. Nature 385 pp. 361 (1997) 1FFH
FtsY-NG of E. coli X-Ray Montoya, G., Svensson, C., Luirink, J., Sinning, I. Crystal structure of the NG domain from the signal-recognition particle receptor FtsY. Nature 385 pp. 365-368 (1997) 1FTS


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